Table of Contents

1. What Is Zofran?
2. Why Do You Feel Nausea During a Hangover?
3. How Zofran for Hangovers Works
4. How You Can Get Zofran for a Hangover

Sometimes you’ve got to pay the piper for an epic night out. That payment comes in the form of a brutal hangover. You know the drill, splitting headache, desert dry mouth, and a stomach that feels like it’s on a constant roller coaster. The only thing you want to do when you’re hungover…is get rid of the hangover! Zofran® can help. Zofran for a hangover isn’t the cure-all we’ve all been wishing for, but it may be able to alleviate your nausea and vomiting.

Does Zofran help a hangover? This article explores that question. We’ll explain what Zofran is, how it works, and why taking Zofran for a hangover can at least help you keep your breakfast down. 

What Is Zofran?

Zofran is the commercial name for ondansetron, a prescription drug that was originally developed to help relieve nausea and vomiting in patients undergoing chemotherapy and radiation treatment. It is also popularly used to ease nausea in post-surgery patients. (Nausea and vomiting are very common side effects of anesthesia.) 

Can you take Zofran for a hangover? While Zofran wasn’t specifically formulated to help you get back on your feet after your best friend’s bachelor or bachelorette party, there’s no contraindication against using it for hangovers. Nausea is nausea, whether it comes from chemo or that third round of Jagerbombs. 

Why Do You Feel Nausea During a Hangover?

The universe is filled with mysteries. What is love? What is the purpose of life? Why do you feel like you’re going to puke your brains out after a night of drinking? So far, we don’t exactly know why nausea and vomiting are such common symptoms of hangovers. 

Researchers do know that alcohol stirs up inflammation throughout the body and irritates the lining of the stomach. It can also cause serotonin (more on that soon) to flood the brain and tell it to expel toxic substances. This all explains why you may end up vomiting during a night of revelry but not why you still feel nausea in the morning, hours after you’ve stopped drinking. 

The best we can guess is that the breakdown of alcohol in your body could release chemicals or substances that trigger nausea and vomiting. The good news is that even if we don’t know exactly what causes hangover nausea, Zofran still works to alleviate your symptoms. 

How Zofran for Hangovers Works 

All that matters is that Zofran for hangovers works, right? Here’s how that happens. It all has to do with a neurotransmitter called serotonin. You might have heard serotonin described as “The Happy Chemical.” However, when it comes to your stomach’s happiness…not so much.

That’s because serotonin plays many roles throughout the body. It regulates

• Mood 
• Sleep
• Memory
• Body temperature
• Learning
• Hunger 
• And more

Serotonin also regulates your digestion. In fact, 90% of serotonin exists in your intestines. When your digestive system senses something toxic in your body, serotonin is the chemical that tells your brain to start feeling nauseous and eventually throw up.

The beauty of Zofran is that it works by blocking serotonin receptors in the brain. When serotonin tries to tell your brain to throw up, the brain doesn’t get the message due to Zofran’s interference. 

How You Can Get Zofran for a Hangover

Zofran sounds pretty good, right? Unfortunately, it can be a little difficult to get, especially on short notice (i.e., when you wake up with a brutal hangover). You’ll need a prescription to get Zofran since it’s not over the counter. It typically comes as an oral tablet or a dissolvable under the tongue tablet.

There is another way. If you know anything about us, you might have guessed it. You can also get Zofran as part of an IV therapy solution. Intravenous therapy provides medicines, vitamins, and minerals within a saline solution that goes directly into the bloodstream. The benefit of using IV therapy is that it bypasses the digestive system and sends the medications and ingredients directly into the body for optimal absorption.

At Rocky Mountain IV, our staff of trained and licensed healthcare professionals can provide an IV that includes Zofran and other vitamins and minerals that may help you recover more quickly from your hangover.

Are There Any Side Effects to Zofran?

Zofran is generally well-tolerated, but some common side effects include 

• Headaches
• Dizziness
• Drowsiness
• Constipation

You shouldn’t take Zofran with certain medications. If you do decide to seek IV therapy through Rocky Mountain IV, make sure to tell your IV specialist about any medications you are taking and any allergies you may have.

What Are the Other Hangover Benefits of IV Therapy?

Using IV therapy for a hangover is a great idea. At Rocky Mountain IV, you can choose to create a customized IV that only includes saline solution and Zofran. This might be the right choice if your main symptom is nausea or vomiting. However, you can also choose one of our IV treatments or add more ingredients to your customized IV.

Not only will the Zofran help alleviate your nausea, but the saline solution itself can play a big role in helping you feel better. The saline solution is a great way to rehydrate after a night on the town. The electrolytes in the IV can also help rebalance your body and help you feel more focused and energized. Our treatments come in a variety of pricing packages.

Other popular IV ingredients include

• Vitamin C
• Vitamin B12
• Toradol (great for headaches)
• Zinc
• Vitamin B complex
• Magnesium
• Glutathione
• And more

We know that the last thing you want to do when you’re dealing with a massive hangover is get in a car and drive to a medical clinic. That’s why our IV professionals come to you. We can provide you with an IV in the comfort and privacy of your home (or your friend’s home if you crashed at their place.) In many cases, a member of our team can show up on your doorstep within an hour of booking an appointment.

What are you waiting for? Don’t let a hangover keep you down. Get some Zofran for your hangover with the help of Rocky Mountain IV.